LCMS/MS provides identification and quantification of drug metabolites based on characteristic molecular fragmentation patterns and specific retention times of the metabolite molecules. This is particularly useful for physicians and other health care providers to determine an appropriate patient-specific regimen for detoxification protocols. Initial screening does not always identify exactly what drug has been found in urine. Confirmation testing, as a more sensitive analysis, employs different technology than the initial screening method. It is used to confirm the presence of a drug, or further pinpoint which drug made the initial result positive. We are continuously reviewing and modifying our offered Test Menu to ensure that the evolving list of illicit and abused drugs can be tested for and monitored by our customers.
Scion Lab Services utilizes enzyme immunoassay (EIA) technique to detect the presence of 8 drugs and 5 drug classes, as well as to determine urine specimen validity. With the combination of liquid chromatography and mass spectroscopy (LCMS-MS), we are able to uniquely identify over 80 drug analytes in urine, thereby enabling us to confirm initial screen results.
Urine Drug Confirmation (LCMS/MS)
Screens do not always detect the presence of drugs or identify which drug may have triggered a positive result. To confirm the presence of a drug, or further pinpoint which drug made the initial result positive, secondary analysis is performed on the same specimen, using highly sensitive LCMS-MS. This form of confirmation testing aids in ensuring that prescribed medication is being taken appropriately and helps to establish a pattern of use. This is helpful information for patients in pain management programs and essential for patients in drug replacement therapy programs.